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Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin

Solution NMR
PDB entry 1ssu coloured by chain, ensemble of 20 models, front view.
PDB entry 1ssu coloured by chain, ensemble of 20 models, side view.
PDB entry 1ssu coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Somatomedin-B
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-137317

Macromolecules

Somatomedin-B
Chain: A
Length: 51 amino acids
Theoretical weight: 5.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04004 (Residues: 20-70; Coverage: 11%)
Gene name: VTN
Pfam: Somatomedin B domain
InterPro:
SCOP: Somatomedin B domain
Somatomedin-B in PDB entry 1ssu, assembly 1, front view.
Somatomedin-B in PDB entry 1ssu, assembly 1, side view.
Somatomedin-B in PDB entry 1ssu, assembly 1, top view.
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