Ligand clusters for UniProt code P11586

Ligand clusters for P11586: C-1-tetrahydrofolate synthase, cytoplasmic from Homo sapiens

1 ligand cluster


Cluster 1. 8 ligand types 13 ligands

Representative protein: 6ecpA

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Ligand

Description

1. Ligand: NAP × 3

Nadp nicotinamide-Adenine-Dinucleotide phosphate

PDB codes: 1dia(A), 1dib(A), 1dig(A).

2. Ligand: NDP × 1

Nadph dihydro-Nicotinamide-Adenine-Dinucleotide phosphate

PDB code: 1a4i(A).

3. Ligand: L34 × 1

4-(7-Amino-9-Hydroxy-1-Oxo-3,3a,4,5-Tetrahydro-2,5,6,8, 9b-Pentaaza-Cyclopenta[a]naphthalen-2-Yl)-
Phenylcarbonyl-Glutamic acid

PDB code: 1dib(A).

4. Ligand: L37 × 1

[[N'-(2,5-Diamino-6-Hydroxy-Pyrimidin-4-Yl)-Ureayl]- Phen-4-Yl]-Carbonyl-Glutamic acid

PDB code: 1dig(A).

5. Ligand: L24 × 1

[[[2-Amino-5,6,7,8-Tetrahydro-4-Hydroxy-Pyrido[2,3- D]pyrimidin-6-Yl]-Ethyl]-Phenyl]-Carbonyl-
Glutamic acid

PDB code: 1dia(A).

6. Ligand: NAP × 3

Nadp nicotinamide-Adenine-Dinucleotide phosphate

PDB codes: 6ecp(A), 6ecq(A), 6ecr(A).

7. Ligand: 21V × 2

N-(4-{2-[(6s)-2-Amino-4-Oxo-1,4,5,6,7,8- Hexahydropyrido[2,3-D]pyrimidin-6-Yl]ethyl}benzoyl)-L-
Glutamic acid

PDB codes: 6ecp(A),

8. Ligand: LUD × 1

N-{4-[(6ar)-3-Amino-1,9-Dioxo-1,2,5,6,6a,7- Hexahydroimidazo[1,5-F]pteridin-8(9h)-Yl]benzene-1-
Carbonyl}-L-Glutamic acid

PDB code: 6ecq(A).