Ligand clusters for UniProt code P00390

Ligand clusters for P00390: Glutathione reductase, mitochondrial OS=Homo sapiens GN=GSR PE=1 SV=2

		Top 6 (of 17) ligand clusters Cluster 1. 22 ligand types 81 ligands Cluster 2. 1 ligand type 2 ligands Cluster 3. 3 ligand types 4 ligands Cluster 4. 2 ligand types 2 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 3 ligand types 3 ligands
Representative protein: 1k4qA

Structures

PDB		Schematic diagram
1k4qA
1bwcA
1graA
1grbA
1dncA
		more ...

Cluster 1 contains 22 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: FAD × 18 Flavin-Adenine dinucleotide PDB codes: 1bwc(A), 1dnc(A), 1gra(A), 1grb(A), 1gre(A), 1grf(A), 1grg(A), 1grt(A), 1gsn(A), 1xan(A), 2aaq(A), 2gh5(A), 2grt(A), 3grs(A), 3grt(A), 4gr1(A), 4grt(A), 5grt(A).
		2. Ligand: NDP × 1 Nadph dihydro-Nicotinamide-Adenine-Dinucleotide phosphate PDB code: 1gra(A).
		3. Ligand: GDS × 1 Oxidized glutathione disulfide PDB code: 2grt(A).
		4. Ligand: GSH × 5 glutathione Glutathione PDB codes: 1dnc(A), 1gre(A), 1gsn(A), 3dk8(A).
		5. Ligand: TS2 × 1 2-Amino-4-[4-(4-Amino-4-Carboxy-Butyrylamino)-5,8,19, 22-Tetraoxo-1,2-Dithia-6,9,13,18,21-Pentaaza- Cyclotetracos-23-Ylcarbamoyl]-Butyric acid PDB code: 3grt(A).
		6. Ligand: TS4 × 1 Glutathionylspermidine disulfide PDB code: 5grt(A).
		7. Ligand: RGS × 1 4n-Malonyl-Cysteinyl-2,4-Diaminobutyrate disulfide PDB code: 4gr1(A).
		8. Ligand: GCG × 1 Bis(gamma-Glutamyl-Cysteinyl-Glycinyl)spermidine PDB code: 4grt(A).
		9. Ligand: ELI × 1 6-(3-Methyl-1,4-Dioxo-1,4-Dihydronaphthalen-2-Yl) hexanoic acid PDB code: 2gh5(A).
		10. Ligand: ACM × 1 Acetamide PDB code: 1grf(A).
		11. Ligand: GOL × 5 Glycerol PDB codes: 2aaq(A), 2gh5(A),
		12. Ligand: AJ3 × 1 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol PDB code: 1bwc(A).
		13. Ligand: PO4 × 13 Phosphate ion PDB codes: 1dnc(A), 1grb(A), 1gre(A), 1grf(A), 1grg(A), 1gsn(A), 2aaq(A), 2gh5(A), 3grs(A), 4gr1(A).
		14. Ligand: FAD × 8 Flavin-Adenine dinucleotide PDB codes: 1grh(A), 1k4q(A), 3djg(X), 3djj(A), 3dk4(A), 3dk8(A), 3dk9(A), 3sqp(A).
		15. Ligand: PO4 × 3 Phosphate ion PDB codes: 1grh(A), 3djj(A),
		16. Ligand: GOL × 4 Glycerol PDB codes: 3djj(A), 3dk8(A).
		17. Ligand: SO4 × 8 Sulfate ion PDB codes: 3dk4(A), 3dk8(A), 3dk9(A), 3sqp(A),
		18. Ligand: NDP × 3 Nadph dihydro-Nicotinamide-Adenine-Dinucleotide phosphate PDB codes: 3djg(X), 3djj(A), 3dk4(A).
		19. Ligand: GSH-GSH × 2 GSH=Glutathione. PDB codes: 1gra(A), 3dk4(A).
		20. Ligand: NAD-NDP × 1 NAD=Nicotinamide-Adenine-Dinucleotide, NDP=Nadph dihydro-Nicotinamide-Adenine-Dinucleotide phosphate. PDB code: 1grb(A).
+ more. Press for full list

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: FAD × 2 Flavin-Adenine dinucleotide PDB codes: 2gh5(A), 3sqp(A).

Cluster 3 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: HXP × 1 3,6-Dihydroxy-Xanthene-9-Propionic acid PDB code: 1xan(A).
		2. Ligand: PO4 × 1 Phosphate ion PDB code: 2aaq(A).
		3. Ligand: 3J8 × 2 5-Methylphenazin-1(5h)-One PDB codes: 3sqp(A),

Cluster 4 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: AUP × 1 2-(2-Phenyl-3-Pyridin-2-Yl-4,5,6,7-Tetrahydro-2h- Isophosphindol-1-Yl)pyridine PDB code: 2aaq(A).
_Au		2. Metal: _AU × 1 PDB code: 2aaq(A).

Cluster 5 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: ELI × 1 6-(3-Methyl-1,4-Dioxo-1,4-Dihydronaphthalen-2-Yl) hexanoic acid PDB code: 2gh5(A).

Cluster 6 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 Glycerol PDB code: 3djj(A).
		2. Ligand: PO4 × 1 Phosphate ion PDB code: 3djj(A).
_Cl		3. Metal: _CL × 1 PDB code: 1bwc(A).