8csl

Electron Microscopy
25Å resolution

Sub-tomogram averaging of erythrocyte ankyrin-1 complex

Released:
Source organism: Homo sapiens
Primary publication:
Architecture of the human erythrocyte ankyrin-1 complex.
Nat Struct Mol Biol 29 706-718 (2022)
PMID: 35835865
Related structures: EMD-26965

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonadecamer (preferred)
PDBe Complex ID:
PDB-CPX-136108 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Ankyrin-1 Chain: A
Molecule details ›
Chain: A
Length: 1881 amino acids
Theoretical weight: 206.52 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P16157 (Residues: 1-1881; Coverage: 100%)
Gene names: ANK, ANK1
Sequence domains:
Band 3 anion transport protein Chains: V, W, Y, Z, e, f, g
Molecule details ›
Chains: V, W, Y, Z, e, f, g
Length: 911 amino acids
Theoretical weight: 101.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02730 (Residues: 1-911; Coverage: 100%)
Gene names: AE1, DI, EPB3, SLC4A1
Sequence domains:
Blood group Rh(CE) polypeptide Chain: K
Molecule details ›
Chain: K
Length: 417 amino acids
Theoretical weight: 45.6 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18577 (Residues: 1-417; Coverage: 100%)
Gene names: RHC, RHCE, RHE
Sequence domains: Ammonium Transporter Family
Ammonium transporter Rh type A Chains: L, Q
Molecule details ›
Chains: L, Q
Length: 409 amino acids
Theoretical weight: 44.23 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q02094 (Residues: 1-409; Coverage: 100%)
Gene names: RH50, RHAG
Sequence domains: Ammonium Transporter Family
Protein 4.2 Chain: X
Molecule details ›
Chain: X
Length: 691 amino acids
Theoretical weight: 77.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P16452 (Residues: 1-691; Coverage: 100%)
Gene names: E42P, EPB42
Sequence domains:
Glycophorin-B Chain: P
Molecule details ›
Chain: P
Length: 91 amino acids
Theoretical weight: 9.79 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P06028 (Residues: 1-91; Coverage: 100%)
Gene names: GPB, GYPB
Sequence domains: Glycophorin A
Glycophorin-A Chains: R, S, T, a, b, c
Molecule details ›
Chains: R, S, T, a, b, c
Length: 150 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02724 (Residues: 1-150; Coverage: 100%)
Gene names: GPA, GYPA
Sequence domains: Glycophorin A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 25Å
Relevant EMDB volumes: EMD-26965