Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134212 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin A chain
Molecule details ›
Chains: A, C
Length: 24 amino acids
Theoretical weight: 2.74 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 24 amino acids
Theoretical weight: 2.74 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
Insulin B chain
Molecule details ›
Chains: B, D
Length: 22 amino acids
Theoretical weight: 2.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 22 amino acids
Theoretical weight: 2.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P01308 (Residues: 25-46; Coverage: 26%)
Insulin receptor subunit alpha
Molecule details ›
Chains: E, F
Length: 917 amino acids
Theoretical weight: 104.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 917 amino acids
Theoretical weight: 104.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P06213 (Residues: 28-956; Coverage: 68%)
Sequence domains:
