Function and Biology

Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1

Source organisms:
Biochemical function: integrin binding
Biological process: cell-cell adhesion
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF03921
Domain description: Intercellular adhesion molecule (ICAM), N-terminal domain
Occurring in:
  1. Intercellular adhesion molecule 1
The deposited structure of PDB entry 6s8u contains 1 copy of Pfam domain PF03921 (Intercellular adhesion molecule (ICAM), N-terminal domain) in Intercellular adhesion molecule 1. Showing 1 copy in chain B.

PF05424
Domain description: Duffy binding domain
Occurring in:
  1. Erythrocyte membrane protein 1
The deposited structure of PDB entry 6s8u contains 1 copy of Pfam domain PF05424 (Duffy binding domain) in Erythrocyte membrane protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003987
Domain description: Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
Occurring in:
  1. Intercellular adhesion molecule 1
IPR003988
Domain description: Intercellular adhesion molecule
Occurring in:
  1. Intercellular adhesion molecule 1
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Intercellular adhesion molecule 1
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Intercellular adhesion molecule 1
IPR047012
Domain description: Intercellular adhesion molecule/vascular cell adhesion molecule
Occurring in:
  1. Intercellular adhesion molecule 1
IPR013768
Domain description: Intercellular adhesion molecule, N-terminal
Occurring in:
  1. Intercellular adhesion molecule 1
IPR008602
Domain description: Duffy-antigen binding domain
Occurring in:
  1. Erythrocyte membrane protein 1
IPR042202
Domain description: Duffy-antigen binding superfamily
Occurring in:
  1. Erythrocyte membrane protein 1