Function and Biology

Humanised RadA mutant HumRadA22 in complex with a recombined BRC repeat 8-2

Source organisms:
Biochemical function: ATP-dependent DNA damage sensor activity
Biological process: DNA recombination
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF00634
Domain description: BRCA2 repeat
Occurring in:
  1. Breast cancer type 2 susceptibility protein
The deposited structure of PDB entry 6hqu contains 7 copies of Pfam domain PF00634 (BRCA2 repeat) in Breast cancer type 2 susceptibility protein. Showing 1 copy in chain I.

InterPro InterPro annotations
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. DNA repair and recombination protein RadA
IPR002093
Domain description: BRCA2 repeat
Occurring in:
  1. Breast cancer type 2 susceptibility protein
IPR020587
Domain description: DNA recombination and repair protein RecA, monomer-monomer interface
Occurring in:
  1. DNA repair and recombination protein RadA
IPR003593
Domain description: AAA+ ATPase domain
Occurring in:
  1. DNA repair and recombination protein RadA
IPR013632
Domain description: DNA recombination and repair protein Rad51-like, C-terminal
Occurring in:
  1. DNA repair and recombination protein RadA
IPR020588
Domain description: DNA recombination and repair protein RecA-like, ATP-binding domain
Occurring in:
  1. DNA repair and recombination protein RadA
IPR011939
Domain description: DNA repair and recombination protein RadB
Occurring in:
  1. DNA repair and recombination protein RadA