Domain

DNA recombination and repair protein Rad51-like, C-terminal (IPR013632)

Short name: DNA_recomb/repair_Rad51_C

Overlapping homologous superfamilies

Domain relationships

  • DNA recombination and repair protein Rad51-like, C-terminal (IPR013632)

Description

This domain is found at the C terminus of DNA repair and recombination protein Rad51, and eukaryotic and archaeal Rad51-like proteins. It is critical for DNA binding [PMID: 15908697]. Rad51 is a homologue of the bacterial RecA protein. Rad51 and RecA share a core ATPase domain.

Unlike eubacteria, several archaeal species have two recA/RAD51-like genes, called RadA and RadB. Among eukaryotes, yeast contain four RAD51-like genes (RAD51, DMC1, RAD55/rhp55, and RAD57/rhp57). In vertebrate animals and plants, there are different RAD51-like genes: RAD51, RAD51B, RAD51C, RAD51D, DMC1, XRCC2, and XRCC3 [PMID: 16798872].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam