› 6frb

X-ray diffraction
1.75Å resolution

F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101

Released:
DOI: 10.2210/pdb6frb/pdb
PDB entry 6frb coloured by chain, front view.
PDB entry 6frb coloured by chain, side view.
PDB entry 6frb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Holland CJ, MacLachlan BJ, Bianchi V, Hesketh SJ, Morgan R, Vickery O, Bulek AM, Fuller A, Godkin A, Sewell AK, Rizkallah PJ, Wells S, Cole DK
OpenAccess logo Front Immunol 9 674 (2018)
PMID: 29696015

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214059 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Human T-Cell Receptor F11 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 202 amino acids
Theoretical weight: 22.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Human T-Cell Receptor F11 beta Chain Chain: B
Molecule details ›
Chain: B
Length: 240 amino acids
Theoretical weight: 27.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21212
Unit cell:
a: 85.16Å b: 115.43Å c: 50.48Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.243
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structural understanding of T cell receptor triggering.
Xu et al. (2020)
2 more

1 mention without citation

In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Holland et al. (2018)