› › Structure analysis

Crystal Structure of C-terminal domain of mouse eRF1 in complex with RNase H domain of RT of Moloney Murine Leukemia Virus

X-ray diffraction
2.8Å resolution
PDB entry 5dmr coloured by chain, front view.
PDB entry 5dmr coloured by chain, side view.
PDB entry 5dmr coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Reverse transcriptase/ribonuclease H and Eukaryotic peptide chain release factor subunit 1
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 13484.44 Å2
Buried surface area: 1297.93 Å2
Dissociation area: 648.97 Å2
Dissociation energy (ΔGdiss): -1.72 kcal/mol
Dissociation entropy (TΔSdiss): 11.3 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136826

Macromolecules

Reverse transcriptase/ribonuclease H
Chain: A
Length: 172 amino acids
Theoretical weight: 18.77 KDa
Source organism: Moloney murine leukemia virus isolate Shinnick
Expression system: Escherichia coli
UniProt:
  • Canonical: P03355 (Residues: 1159-1330; Coverage: 10%)
Gene name: gag-pol
Pfam: RNase H
InterPro:
CATH: Ribonuclease H-like superfamily/Ribonuclease H
Reverse transcriptase/ribonuclease H in PDB entry 5dmr, assembly 1, front view.
Reverse transcriptase/ribonuclease H in PDB entry 5dmr, assembly 1, side view.
Reverse transcriptase/ribonuclease H in PDB entry 5dmr, assembly 1, top view.
Molecule details ›

Search similar proteins

Eukaryotic peptide chain release factor subunit 1
Chain: B
Length: 162 amino acids
Theoretical weight: 18.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8BWY3 (Residues: 276-437; Coverage: 37%)
Gene name: Etf1
Pfam: eRF1 domain 3
InterPro:
Eukaryotic peptide chain release factor subunit 1 in PDB entry 5dmr, assembly 1, front view.
Eukaryotic peptide chain release factor subunit 1 in PDB entry 5dmr, assembly 1, side view.
Eukaryotic peptide chain release factor subunit 1 in PDB entry 5dmr, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links