› › Structure analysis

Human enterovirus 71 uncoating intermediate captured at atomic resolution

X-ray diffraction
3.801Å resolution
PDB entry 4n43 coloured by chain, front view.
PDB entry 4n43 coloured by chain, side view.
PDB entry 4n43 coloured by chain, top view.
Source organism: Enterovirus A71
Assembly composition:
hetero 180-mer (preferred)
Entry contents: 3 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero 180-mer
Accessible surface area: 1186692.32 Å2
Buried surface area: 1278277.76 Å2
Dissociation area: 197,127.43 Å2
Dissociation energy (ΔGdiss): 2,579.25 kcal/mol
Dissociation entropy (TΔSdiss): 389.33 kcal/mol
Symmetry number: 60
PDBe Complex ID: PDB-CPX-126088

Macromolecules

Capsid protein VP1
Chain: A
Length: 297 amino acids
Theoretical weight: 32.7 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: M9XM90 (Residues: 566-862; Coverage: 14%)
Pfam: picornavirus capsid protein
InterPro:
CATH: Jelly Rolls
Capsid protein VP1 in PDB entry 4n43, assembly 1, front view.
Capsid protein VP1 in PDB entry 4n43, assembly 1, side view.
Capsid protein VP1 in PDB entry 4n43, assembly 1, top view.
Molecule details ›

Search similar proteins

Capsid protein VP2
Chain: B
Length: 254 amino acids
Theoretical weight: 27.73 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: Q9WQJ0 (Residues: 70-323; Coverage: 12%)
Pfam: picornavirus capsid protein
InterPro:
CATH: Jelly Rolls
Capsid protein VP2 in PDB entry 4n43, assembly 1, front view.
Capsid protein VP2 in PDB entry 4n43, assembly 1, side view.
Capsid protein VP2 in PDB entry 4n43, assembly 1, top view.
Molecule details ›

Search similar proteins

Capsid protein VP3
Chain: C
Length: 242 amino acids
Theoretical weight: 26.44 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: Q9WPJ0 (Residues: 324-565; Coverage: 11%)
Pfam: picornavirus capsid protein
InterPro:
CATH: Jelly Rolls
Capsid protein VP3 in PDB entry 4n43, assembly 1, front view.
Capsid protein VP3 in PDB entry 4n43, assembly 1, side view.
Capsid protein VP3 in PDB entry 4n43, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links