Function and Biology

Crystal structure of SUMO E3 Ligase PIAS3

Source organism: Homo sapiens
Biochemical function: zinc ion binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF02891
Domain description: MIZ/SP-RING zinc finger
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
The deposited structure of PDB entry 4mvt contains 4 copies of Pfam domain PF02891 (MIZ/SP-RING zinc finger) in E3 SUMO-protein ligase PIAS3. Showing 1 copy in chain A.

PF14324
Domain description: PINIT domain
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
The deposited structure of PDB entry 4mvt contains 4 copies of Pfam domain PF14324 (PINIT domain) in E3 SUMO-protein ligase PIAS3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004181
Domain description: Zinc finger, MIZ-type
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
IPR023321
Domain description: PINIT domain
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
IPR038654
Domain description: PINIT domain superfamily
Occurring in:
  1. E3 SUMO-protein ligase PIAS3

Structure domains

CATH CATH domains
3.30.40.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Herpes Virus-1
Homology: Zinc/RING finger domain, C3HC4 (zinc finger)
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
The deposited structure of PDB entry 4mvt contains 4 copies of CATH domain 3.30.40.10 (Herpes Virus-1) in E3 SUMO-protein ligase PIAS3. Showing 1 copy in chain A.
2.60.120.780
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: PINIT domain
Occurring in:
  1. E3 SUMO-protein ligase PIAS3
The deposited structure of PDB entry 4mvt contains 4 copies of CATH domain 2.60.120.780 (Jelly Rolls) in E3 SUMO-protein ligase PIAS3. Showing 1 copy in chain A.