This entry represents the PINIT domain, which serves as a scaffold to coordinate PCNA to promote SUMO conjugation to both consensus and nonconsensus lysine side chains [PMID: 19748360]. This domain is found in the PIAS family of proteins [PMID: 14596924].
Yunus AA, Lima CD.
Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA. Mol. Cell 35 669-82 2009
Duval D, Duval G, Kedinger C, Poch O, Boeuf H.
The 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L. FEBS Lett. 554 111-8 2003
Signatures from InterPro member databases are used to construct an entry.