› › Function and Biology

Crystal structure of the response regulator KdpE complexed to DNA in an active-like conformation

Source organism: Escherichia coli K-12
Biochemical function: protein homodimerization activity
Biological process: positive regulation of DNA-templated transcription
Cellular component: protein-DNA complex

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00486
Domain description: Transcriptional regulatory protein, C terminal
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
The deposited structure of PDB entry 4kny contains 2 copies of Pfam domain PF00486 (Transcriptional regulatory protein, C terminal) in KDP operon transcriptional regulatory protein KdpE. Showing 1 copy in chain B.

PF00072
Domain description: Response regulator receiver domain
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
The deposited structure of PDB entry 4kny contains 2 copies of Pfam domain PF00072 (Response regulator receiver domain) in KDP operon transcriptional regulatory protein KdpE. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001867
Domain description: OmpR/PhoB-type DNA-binding domain
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
IPR001789
Domain description: Signal transduction response regulator, receiver domain
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
IPR039420
Domain description: Transcriptional regulatory protein WalR-like
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
IPR011006
Domain description: CheY-like superfamily
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE

Structure domains

CATH CATH domains
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
The deposited structure of PDB entry 4kny contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in KDP operon transcriptional regulatory protein KdpE. Showing 1 copy in chain B.
3.40.50.2300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. KDP operon transcriptional regulatory protein KdpE
The deposited structure of PDB entry 4kny contains 2 copies of CATH domain 3.40.50.2300 (Rossmann fold) in KDP operon transcriptional regulatory protein KdpE. Showing 1 copy in chain B.

Quick links