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Structural Basis of Histone H4 Recognition by p55

X-ray diffraction
2.9Å resolution
PDB entry 3c99 coloured by chain, front view.
PDB entry 3c99 coloured by chain, side view.
PDB entry 3c99 coloured by chain, top view.
Source organism: Drosophila melanogaster
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Chromatin assembly factor 1 p55 subunit
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Multimeric state: monomeric
Accessible surface area: 17517.77 Å2
Buried surface area: 987.63 Å2
Dissociation area: 39.15 Å2
Dissociation energy (ΔGdiss): 2.99 kcal/mol
Dissociation entropy (TΔSdiss): 0.88 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-173197
Assembly 2
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Assembly Name: Chromatin assembly factor 1 p55 subunit
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Multimeric state: homo dimer
Accessible surface area: 32305.44 Å2
Buried surface area: 4706.87 Å2
Dissociation area: 1,391.04 Å2
Dissociation energy (ΔGdiss): 18.12 kcal/mol
Dissociation entropy (TΔSdiss): 14.11 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-173199

Macromolecules

Chromatin assembly factor 1 p55 subunit
Chain: A
Length: 432 amino acids
Theoretical weight: 48.82 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q24572 (Residues: 1-430; Coverage: 100%)
Gene names: CG4236, Caf1, Caf1-55
Pfam:
InterPro:
CATH: YVTN repeat-like/Quinoprotein amine dehydrogenase
Chromatin assembly factor 1 p55 subunit in PDB entry 3c99, assembly 1, front view.
Chromatin assembly factor 1 p55 subunit in PDB entry 3c99, assembly 1, side view.
Chromatin assembly factor 1 p55 subunit in PDB entry 3c99, assembly 1, top view.
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