2y65

X-ray diffraction
2.2Å resolution

Crystal structure of Drosophila melanogaster kinesin-1 motor domain dimer-tail complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147896 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kinesin heavy chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 365 amino acids
Theoretical weight: 40.89 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17210 (Residues: 1-365; Coverage: 37%)
Gene names: CG7765, Khc, kin
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain
Kinesin heavy chain Chains: W, X, Y
Molecule details ›
Chains: W, X, Y
Length: 20 amino acids
Theoretical weight: 1.91 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P17210 (Residues: 937-952; Coverage: 2%)
Gene names: CG7765, Khc, kin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2221
Unit cell:
a: 113.765Å b: 190.714Å c: 145.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.252
Expression systems:
  • Escherichia coli BL21
  • Escherichia coli