› 2ncd

X-ray diffraction
2.5Å resolution

NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER

Released:
DOI: 10.2210/pdb2ncd/pdb
PDB entry 2ncd coloured by chain, front view.
PDB entry 2ncd coloured by chain, side view.
PDB entry 2ncd coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Direction determination in the minus-end-directed kinesin motor ncd.
Sablin EP, Case RB, Dai SC, Hart CL, Ruby A, Vale RD, Fletterick RJ
Nature 395 813-6 (1998)
PMID: 9796817

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein claret segregational Chain: A
Molecule details ›
Chain: A
Length: 420 amino acids
Theoretical weight: 47.74 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P20480 (Residues: 281-700; Coverage: 60%)
Gene names: CA(ND), CG7831, ncd
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P6122
Unit cell:
a: 123Å b: 123Å c: 121.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.226 0.27
Expression system: Escherichia coli

Quick links

Citations

33 review citations

Molecular motors.
Schliwa et al. (2003)
32 more

21 mentions without citation

Lessons learned from UvrD helicase: mechanism for directional movement.
Yang W. (2010)
20 more