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Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00084
Domain description: Sushi repeat (SCR repeat)
Occurring in:
  1. Complement receptor type 2
The deposited structure of PDB entry 1w2s contains 2 copies of Pfam domain PF00084 (Sushi repeat (SCR repeat)) in Complement receptor type 2. Showing 2 copies in chain B.

PF07678
Domain description: A-macroglobulin TED domain
Occurring in:
  1. Complement C3d fragment
The deposited structure of PDB entry 1w2s contains 1 copy of Pfam domain PF07678 (A-macroglobulin TED domain) in Complement C3d fragment. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000436
Domain description: Sushi/SCR/CCP domain
Occurring in:
  1. Complement receptor type 2
IPR035976
Domain description: Sushi/SCR/CCP superfamily
Occurring in:
  1. Complement receptor type 2
IPR047565
Domain description: Alpha-macroglobulin-like, thiol-ester bond-forming region
Occurring in:
  1. Complement C3d fragment
IPR011626
Domain description: Alpha-macroglobulin-like, TED domain
Occurring in:
  1. Complement C3d fragment
IPR008930
Domain description: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Occurring in:
  1. Complement C3d fragment

Structure domain

SCOP SCOP annotations
57536
Class: Small proteins
Fold: Complement control module/SCR domain
Superfamily: Complement control module/SCR domain
Occurring in:
  1. Complement receptor type 2
The deposited structure of PDB entry 1w2s contains 2 copies of SCOP domain 57536 (Complement control module/SCR domain) in Complement receptor type 2. Showing 2 copies in chain B.
48251
Class: All alpha proteins
Fold: alpha/alpha toroid
Superfamily: Terpenoid cyclases/Protein prenyltransferases
Occurring in:
  1. Complement C3d fragment
The deposited structure of PDB entry 1w2s contains 1 copy of SCOP domain 48251 (Complement components) in Complement C3d fragment. Showing 1 copy in chain A.

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