1w2s

X-ray solution scattering

Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 34.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01024 (Residues: 995-1287, 1288-1299; Coverage: 19%)
Gene names: C3, CPAMD1
Complement receptor type 2 Chain: B
Molecule details ›
Chain: B
Length: 142 amino acids
Theoretical weight: 15.61 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P20023 (Residues: 20-153; Coverage: 13%)
Gene names: C3DR, CR2
Sequence domains: Sushi repeat (SCR repeat)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Expression systems:
  • Escherichia coli BL21
  • Komagataella pastoris