› › Structure analysis

INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY

X-ray diffraction
2.8Å resolution
PDB entry 1lgc coloured by chain, front view.
PDB entry 1lgc coloured by chain, side view.
PDB entry 1lgc coloured by chain, top view.
Source organism: Lathyrus ochrus
Assembly composition:
hetero hexamer (preferred)
Entry contents: 3 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Multimeric state: hetero hexamer
Accessible surface area: 18483.51 Å2
Buried surface area: 23460.62 Å2
Dissociation area: 1,618.48 Å2
Dissociation energy (ΔGdiss): -27.75 kcal/mol
Dissociation entropy (TΔSdiss): 16.76 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-137412
Assembly 2 (preferred)
Download    3D Visualisation
Multimeric state: hetero hexamer
Accessible surface area: 18450.04 Å2
Buried surface area: 23377.95 Å2
Dissociation area: 1,588.45 Å2
Dissociation energy (ΔGdiss): -24.61 kcal/mol
Dissociation entropy (TΔSdiss): 17.17 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-137412

Macromolecules

Lectin beta-1 and beta-2 chains
Chains: A, C, E
Length: 181 amino acids
Theoretical weight: 19.86 KDa
Source organism: Lathyrus ochrus
Expression system: Not provided
UniProt:
  • Canonical: P04122 (Residues: 1-181; Coverage: 100%)
Pfam: Legume lectin domain
InterPro:
CATH: Jelly Rolls
SCOP: Legume lectins
Lectin beta-1 and beta-2 chains in PDB entry 1lgc, assembly 2, front view.
Lectin beta-1 and beta-2 chains in PDB entry 1lgc, assembly 2, side view.
Lectin beta-1 and beta-2 chains in PDB entry 1lgc, assembly 2, top view.
Molecule details ›

Search similar proteins

DIPEPTIDE
Chains: H, I, J
Length: 2 amino acids
Theoretical weight: 260 Da
DIPEPTIDE in PDB entry 1lgc, assembly 2, front view.
DIPEPTIDE in PDB entry 1lgc, assembly 2, side view.
DIPEPTIDE in PDB entry 1lgc, assembly 2, top view.
Molecule details ›

Search similar proteins

Mannose/glucose-specific lectin alpha 2 chain
Chains: B, D, F
Length: 53 amino acids
Theoretical weight: 5.93 KDa
Source organism: Lathyrus ochrus
Expression system: Not provided
UniProt:
  • Canonical: P12307 (Residues: 1-53; Coverage: 100%)
Pfam: Legume lectin domain
InterPro:
SCOP: Legume lectins
Mannose/glucose-specific lectin alpha 2 chain in PDB entry 1lgc, assembly 2, front view.
Mannose/glucose-specific lectin alpha 2 chain in PDB entry 1lgc, assembly 2, side view.
Mannose/glucose-specific lectin alpha 2 chain in PDB entry 1lgc, assembly 2, top view.
Molecule details ›

Search similar proteins

Quick links