› 4p1h

X-ray diffraction
1.5Å resolution

Crystal structure of wild type Hypocrea jecorina Cel7a in a monoclinic crystal form

Released:
DOI: 10.2210/pdb4p1h/pdb
PDB entry 4p1h coloured by chain, front view.
PDB entry 4p1h coloured by chain, side view.
PDB entry 4p1h coloured by chain, top view.
Source organism: Trichoderma reesei QM6a
Entry authors: Bodenheimer AB, Cuneo MJ, Swartz PD, Myles DA, Meilleur F

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158661 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exoglucanase 1 Chain: A
Molecule details ›
Chain: A
Length: 432 amino acids
Theoretical weight: 45.87 KDa
Source organism: Trichoderma reesei QM6a
UniProt:
  • Canonical: P62694 (Residues: 18-449; Coverage: 87%)
Gene name: cbh1
Sequence domains: Glycosyl hydrolase family 7
Structure domains: Glycoside hydrolase, family 7, domain

Ligands and Environments

3 bound ligands:
Ligand NAG 2 x NAG
Ligand SM 1 x SM
Ligand BEN 1 x BEN
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 152.459Å b: 44.904Å c: 57.567Å
α: 90° β: 101.25° γ: 90°
R-values:
R R work R free
0.16 0.159 0.19

Quick links

Citations

1 mention without citation

A unique mid-sequence linker used to multimerize the lipid-phosphatidylserine (PS) binding peptide-peptoid hybrid PPS1.
Shukla et al. (2017)