› 2zsm

X-ray diffraction
2.3Å resolution

Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from Aeropyrum pernix, hexagonal form

Released:
DOI: 10.2210/pdb2zsm/pdb
PDB entry 2zsm coloured by chain, front view.
PDB entry 2zsm coloured by chain, side view.
PDB entry 2zsm coloured by chain, top view.
Source organism: Aeropyrum pernix
Entry authors: Mizutani H, Kunishima N

Function and Biology Details

Reaction catalysed: 
(S)-4-amino-5-oxopentanoate = 5-aminolevulinate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate-1-semialdehyde 2,1-aminomutase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 434 amino acids
Theoretical weight: 46.53 KDa
Source organism: Aeropyrum pernix
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y9I9 (Residues: 2-429; Coverage: 100%)
Gene names: APE_2299.1, hemL
Sequence domains: Aminotransferase class-III
Structure domains:

Ligands and Environments


Cofactor: Ligand PMP 3 x PMP
1 bound ligand:
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P6522
Unit cell:
a: 123.39Å b: 123.39Å c: 356.443Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.211
Expression system: Escherichia coli

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