Sample Studies Relationship List

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            "type": "studies",
            "id": "MGYS00002264",
            "attributes": {
                "bioproject": "PRJNA264728",
                "samples-count": 7,
                "accession": "MGYS00002264",
                "is-private": false,
                "last-update": "2020-12-08T10:07:14",
                "secondary-accession": "SRP049210",
                "centre-name": "JCVI",
                "public-release-date": null,
                "study-abstract": "Dental caries, one of the most globally widespread infectious diseases is intimately linked to pH dynamics. In supragingival plaque, after the addition of a carbohydrate source, bacteria rapidly decrease the pH which then subsequently recovers. In this project we studied gene transcription in naturally diverse saliva-derived in vitro grown biofilms as they were amended with sugar (corresponding to a dietary intake of carbohydrates). We applied an in vitro biofilm model system that was previously determined to be functionally and taxonomically robust and representative of health-associated dental plaque. The major goal was to characterize critical gene expression mechanisms supporting the understudied pH-recovery stage associated with health. This study provides a solid baseline for defining healthy and disease-like states and highlights the power of moving beyond single and dual species applications to capture key players and their orchestrated metabolic activities within a human oral microbiome model.",
                "study-name": "Gene expression anlayses of saliva-derived in vitro biofilms during carbohydrate fermentation and pH stress",
                "data-origination": "HARVESTED"
            },
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                    "data": [
                        {
                            "type": "biomes",
                            "id": "root:Host-associated:Arthropoda:Digestive system:Oral:Saliva",
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