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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A0N8EUF1",
"id": "A0A0N8EUF1_HETGA",
"source_organism": {
"taxId": "10181",
"scientificName": "Heterocephalus glaber",
"fullName": "Heterocephalus glaber (Naked mole rat)"
},
"name": "rRNA methyltransferase 2, mitochondrial",
"description": [
"S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3. Essential for late-stage assembly of mtLSU required for efficient translation of mitochondrial DNA encoded proteins; methyltransferase activity is not required for this function. Essential for mitochondrial respiratory function"
],
"length": 246,
"sequence": "MAGYWKLVCASLFCERFHTAAQHYKGRTGAEHLWLMRHLKDPYVKAAKVECYRCRSAFKLLEMNEKHGILRPGLRVLDCGAAPGAWSQVAVQRVNATGADPSFPVGFVLGVDLLHIHPLEGATFLSPADVTDPRTFQRIMELLPCGKADVILSDMAPNATGIRDLDHDRLISMCLSLLDMAPDILHPGGTVLCKTWAGSQSRRLQKRLTEEFQNTRTIKPEASRKESSEVYFLATQYRRRKGSVKQ",
"proteome": null,
"gene": "FTSJ2",
"go_terms": [
{
"identifier": "GO:0008168",
"name": "methyltransferase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0001510",
"name": "RNA methylation",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0032259",
"name": "methylation",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "71a5d42e748b06cd2d42035318a449fe592a7c1a",
"counters": {
"domain_architectures": 26600,
"entries": 10,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"pirsf": 1,
"panther": 1,
"hamap": 1,
"pfam": 1,
"interpro": 4
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 26600
}
}
}