EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:9648 |
| ChEBI Name | tramadol |
| Stars | |
| Definition | A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Grünenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia. |
| Last Modified | 22 February 2017 |
| Formula | C16H25NO2 |
| Net Charge | 0 |
| Average Mass | 263.375 |
| Monoisotopic Mass | 263.18853 |
| Roles Classification |
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| ChEBI Ontology |
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| IUPAC Name |
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| rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol |
| INNs | Source |
|---|---|
| tramadol | WHO MedNet |
| tramadol | WHO MedNet |
| tramadol | WHO MedNet |
| tramadolum | DrugBank |
| Synonyms | Source |
|---|---|
| (±)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol | ChEBI |
| U-26225A | ChEBI |
| CG-315E | ChEBI |
| E-265 | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:2943832 | Reaxys |
| CAS:27203-92-5 | KEGG COMPOUND |
| CAS:27203-92-5 | ChemIDplus |
| Citations |
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