CHEBI:94563 - benzydamine

ChEBI IDCHEBI:94563
ChEBI Namebenzydamine
Stars
DefinitionA member of the class of indazoles carrying benzyl and 3-(dimethylamino)propyl groups at positions 1 and 3 respectively. A locally-acting nonsteroidal anti-inflammatory drug that also exhibits local anaesthetic and analgesic properties.
Last Modified8 May 2017
DownloadsMolfile
FormulaC19H23N3O
Net Charge0
Average Mass309.413
Monoisotopic Mass309.18411
SMILESCN(C)CCCOc1nn(Cc2ccccc2)c2ccccc12
InChIInChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3
InChIKeyCNBGNNVCVSKAQZ-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Applications:
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
hallucinogen  Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
local anaesthetic  Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
benzydamine (CHEBI:94563) has role analgesic (CHEBI:35480)
benzydamine (CHEBI:94563) has role central nervous system stimulant (CHEBI:35337)
benzydamine (CHEBI:94563) has role hallucinogen (CHEBI:35499)
benzydamine (CHEBI:94563) has role local anaesthetic (CHEBI:36333)
benzydamine (CHEBI:94563) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
benzydamine (CHEBI:94563) is a aromatic ether (CHEBI:35618)
benzydamine (CHEBI:94563) is a indazoles (CHEBI:38769)
benzydamine (CHEBI:94563) is a tertiary amino compound (CHEBI:50996)
benzydamine (CHEBI:94563) is conjugate base of benzydamine(1+) (CHEBI:134500)
Incoming Relation(s)
benzydamine(1+) (CHEBI:134500) is conjugate acid of benzydamine (CHEBI:94563)
IUPAC Name 
3-[(1-benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-aminie
INNs  Source
benzydamineKEGG DRUG
benzydamineChemIDplus
benzydaminumChemIDplus
bencidaminaChemIDplus
Synonyms  Source
benzindamineDrugCentral
benzidamineDrugCentral
benzydamideDrugCentral
N,N-dimethyl-3-[[1-(phenylmethyl)-3-indazolyl]oxy]-1-propanamineDrugCentral
1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazoleChemIDplus
Manual XrefsDatabases
LSM-5423LINCS
3881DrugCentral
D07516KEGG DRUG
BenzydamineWikipedia
Registry NumbersSources
Reaxys:896536Reaxys
CAS:642-72-8KEGG DRUG
CAS:642-72-8ChemIDplus
CAS:642-72-8NIST Chemistry WebBook
Citations