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CHEBI:94373 - mosapride
| ChEBI ID | CHEBI:94373 |
| ChEBI Name | mosapride |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. |
| Last Modified | 20 January 2021 |
| Formula | C21H25ClFN3O3 |
| Net Charge | 0 |
| Average Mass | 421.900 |
| Monoisotopic Mass | 421.15685 |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. |
| Applications: | serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. gastrointestinal drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| mosapride (CHEBI:94373) has part (R)-mosapride (CHEBI:167205) |
| mosapride (CHEBI:94373) has part (S)-mosapride (CHEBI:167206) |
| mosapride (CHEBI:94373) has role gastrointestinal drug (CHEBI:55324) |
| mosapride (CHEBI:94373) has role serotonergic agonist (CHEBI:35941) |
| mosapride (CHEBI:94373) is a racemate (CHEBI:60911) |
| INNs | Source |
|---|---|
| mosapridum | WHO MedNet |
| mosapride | WHO MedNet |
| mosapride | WHO MedNet |
| mosaprida | WHO MedNet |
| Synonyms | Source |
|---|---|
| racemic mosapride | ChEBI |
| (RS)-mosapride | ChEBI |
| rac-mosapride | ChEBI |
| (±)-mosapride | ChEBI |
| (±)-4-amino-5-chloro-2-ethoxy-N-((4-(p-fluorobenzyl)-2-morpholinyl)methyl)benzamide | ChemIDplus |
| Citations |
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