T-2 toxin (CHEBI:9381)

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CHEBI:9381 - T-2 toxin

ChEBI ID	CHEBI:9381
ChEBI Name	T-2 toxin
Stars
Definition	A trichothecene mycotoxin produced by fungi of the genus Fusarium . It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals.
Last Modified	23 November 2020
Downloads	Molfile

Formula	C24H34O9
Net Charge	0
Average Mass	466.527
Monoisotopic Mass	466.22028
SMILES	[H][C@@]12C=C(C)[C@@H](OC(=O)CC(C)C)C[C@]1(COC(C)=O)[C@@]1(C)[C@H](OC(C)=O)[C@@H](O)[C@@]([H])(O2)[C@@]12CO2
InChI	InChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
InChIKey	BXFOFFBJRFZBQZ-QYWOHJEZSA-N

Wikipedia

Species of Metabolite	Component	Source	Comments
Fusarium graminearum (ncbitaxon:5518)	-	PubMed (16604118)	Strain: Z-3639
Fusarium sporotrichioides (ncbitaxon:5514)	-	PubMed (16604118)	Strain: NRRL3299

Roles Classification

Chemical Role:

environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects.

Biological Roles:

apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

neurotoxin A poison that interferes with the functions of the nervous system.

cardiotoxic agent A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes.

DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA.

mycotoxin Poisonous substance produced by fungi.

fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.

mycotoxin Poisonous substance produced by fungi.

ChEBI Ontology

Outgoing Relation(s)
	T-2 toxin (CHEBI:9381) has functional parent HT-2 toxin (CHEBI:138861)
	T-2 toxin (CHEBI:9381) has role apoptosis inducer (CHEBI:68495)
	T-2 toxin (CHEBI:9381) has role cardiotoxic agent (CHEBI:50912)
	T-2 toxin (CHEBI:9381) has role DNA synthesis inhibitor (CHEBI:59517)
	T-2 toxin (CHEBI:9381) has role environmental contaminant (CHEBI:78298)
	T-2 toxin (CHEBI:9381) has role fungal metabolite (CHEBI:76946)
	T-2 toxin (CHEBI:9381) has role mycotoxin (CHEBI:25442)
	T-2 toxin (CHEBI:9381) has role neurotoxin (CHEBI:50910)
	T-2 toxin (CHEBI:9381) is a acetate ester (CHEBI:47622)
	T-2 toxin (CHEBI:9381) is a organic heterotetracyclic compound (CHEBI:38163)
	T-2 toxin (CHEBI:9381) is a trichothecene (CHEBI:55517)

IUPAC Name
4β,15-bis(acetyloxy)-3α-hydroxy-12,13-epoxytrichothec-9-en-8α-yl 3-methylbutanoate

Synonyms	Source
3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-δ-9-trichothecene	ChemIDplus
(3α,4β,8α)-12,13-epoxy-4,15-diacetate 8-(3-methylbutanoate)trichothec-9-ene-3,4,8,15-tetrol	ChEBI
4β,15-diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene	ChEBI
fusariotoxine T2	ChemIDplus
fusariotoxin T 2	ChemIDplus
fusariotoxin T-2	ChEBI

Manual Xrefs	Databases
4447526	ChemSpider
C00003192	KNApSAcK
C09738	KEGG COMPOUND
CPD-18416	MetaCyc
FDB015515	FooDB
HMDB0036600	HMDB
T-2_mycotoxin	Wikipedia

Registry Numbers	Sources
Reaxys:3575695	Reaxys
CAS:21259-20-1	ChemIDplus
CAS:21259-20-1	NIST Chemistry WebBook

Citations