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CHEBI:91784 - eliprodil
| ChEBI ID | CHEBI:91784 |
| ChEBI Name | eliprodil |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties. |
| Last Modified | 29 September 2021 |
| Formula | C20H23ClFNO |
| Net Charge | 0 |
| Average Mass | 347.860 |
| Monoisotopic Mass | 347.14522 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. |
| Applications: | neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| eliprodil (CHEBI:91784) has part (R)-eliprodil (CHEBI:180648) |
| eliprodil (CHEBI:91784) has part (S)-eliprodil (CHEBI:180649) |
| eliprodil (CHEBI:91784) has role calcium channel blocker (CHEBI:38215) |
| eliprodil (CHEBI:91784) has role geroprotector (CHEBI:176497) |
| eliprodil (CHEBI:91784) has role neuroprotective agent (CHEBI:63726) |
| eliprodil (CHEBI:91784) has role NMDA receptor antagonist (CHEBI:60643) |
| eliprodil (CHEBI:91784) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol |
| INNs | Source |
|---|---|
| eliprodil | WHO MedNet |
| eliprodil | WHO MedNet |
| éliprodil | WHO MedNet |
| eliprodilum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (±)-eliprodil | ChEBI |
| rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol | IUPAC |
| (RS)-eliprodil | ChEBI |
| racemic eliprodil | ChEBI |
| SL 820715 | ChEBI |
| SL-82,0715 | ChEBI |
| Registry Numbers | Sources |
|---|---|
| CAS:119431-25-3 | ChemIDplus |
| Citations |
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