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CHEBI:91749 - tianeptine
| ChEBI ID | CHEBI:91749 |
| ChEBI Name | tianeptine |
| Stars | |
| Definition | A racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs). |
| Last Modified | 28 February 2022 |
| Formula | C21H25ClN2O4S |
| Net Charge | 0 |
| Average Mass | 436.950 |
| Monoisotopic Mass | 436.12236 |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | mu-opioid receptor agonist A compound that exhibits agonist activity at the μ-opioid receptor. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. second generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements. mu-opioid receptor agonist A compound that exhibits agonist activity at the μ-opioid receptor. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| tianeptine (CHEBI:91749) has part (R)-tianeptine (CHEBI:190007) |
| tianeptine (CHEBI:91749) has part (S)-tianeptine (CHEBI:190006) |
| tianeptine (CHEBI:91749) has role antidepressant (CHEBI:35469) |
| tianeptine (CHEBI:91749) has role antipsychotic agent (CHEBI:35476) |
| tianeptine (CHEBI:91749) has role anxiolytic drug (CHEBI:35474) |
| tianeptine (CHEBI:91749) has role second generation antipsychotic (CHEBI:65191) |
| tianeptine (CHEBI:91749) has role μ-opioid receptor agonist (CHEBI:55322) |
| tianeptine (CHEBI:91749) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid |
| INNs | Source |
|---|---|
| tianeptina | WHO MedNet |
| tianeptine | WHO MedNet |
| tianeptine | WHO MedNet |
| tianeptinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 7-{[(11RS)-3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl]amino}heptanoic acid | IUPAC |
| (±)-7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide | ChEBI |
| rac-tianeptine | ChEBI |
| Gas station heroin | ChEMBL |
| JNJ-39823277 | ChEMBL |
| racemic tianeptine | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| 2650 | DrugCentral |
| 62102 | ChemSpider |
| D02575 | KEGG DRUG |
| HMDB0042038 | HMDB |
| LSM-1626 | LINCS |
| Tianeptine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| CAS:72797-41-2 | ChemIDplus |
| Citations |
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