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CHEBI:9011 - salmeterol

ChEBI IDCHEBI:9011
ChEBI Namesalmeterol
Stars
DefinitionA racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other β2 agonists, it binds to the exo-site domain of β2 receptors, producing a slow onset of action and prolonged activation.
Last Modified22 February 2017
FormulaC25H37NO4
Net Charge0
Average Mass415.566
Monoisotopic Mass415.27226
Wikipedia
Roles Classification
Biological Role:
beta-adrenergic agonist  An agent that selectively binds to and activates β-adrenergic receptors.
Applications:
beta-adrenergic agonist  An agent that selectively binds to and activates β-adrenergic receptors.
bronchodilator agent  An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
ChEBI Ontology
Outgoing Relation(s)
salmeterol (CHEBI:9011) has part (R)-salmeterol (CHEBI:64062)
salmeterol (CHEBI:9011) has part (S)-salmeterol (CHEBI:64063)
salmeterol (CHEBI:9011) has role bronchodilator agent (CHEBI:35523)
salmeterol (CHEBI:9011) has role β-adrenergic agonist (CHEBI:35522)
salmeterol (CHEBI:9011) is a racemate (CHEBI:60911)
INNs  Source
salmeterolChemIDplus
salmeterolumChemIDplus
salmeterolWHO MedNet
salmétérolWHO MedNet
Synonyms  Source
SalmeterolKEGG COMPOUND
(±)-salmeterolChEBI
(RS)-4-hydroxy-α1-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanolChEBI
(±)-4-hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-α,α1-diolChEBI
(RS)-salmeterolChEBI
Manual XrefsDatabases
C07241KEGG COMPOUND
D05792KEGG DRUG
DB00938DrugBank
DE3414752Patent
US4992474Patent
SalmeterolWikipedia
HMDB0015073HMDB
Registry NumbersSources
CAS:89365-50-4KEGG COMPOUND
CAS:89365-50-4ChemIDplus
Citations