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CHEBI:87715 - prasugrel
| ChEBI ID | CHEBI:87715 |
| ChEBI Name | prasugrel |
| Stars | |
| Definition | A racemate comprising equal amounts of (R)- and (S)-prasugrel. Used (as its hydrochloride salt) to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. |
| Last Modified | 22 February 2017 |
| Submitter | Steve |
| Formula | C20H20FNO3S |
| Net Charge | 0 |
| Average Mass | 373.443 |
| Monoisotopic Mass | 373.11479 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antiviral agent A substance that destroys or inhibits replication of viruses. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. P2Y12 receptor antagonist An antagonist at the P2Y12 receptor platelet glycoprotein-IIb/IIIa receptor antagonist Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. renoprotective agent Any compound that is able to prevent damage to the kidneys. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. anticoagulant An agent that prevents blood clotting. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. anti-asthmatic agent Any compound that has anti-asthmatic effects. platelet glycoprotein-IIb/IIIa receptor antagonist Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prasugrel (CHEBI:87715) has part (R)-prasugrel (CHEBI:87725) |
| prasugrel (CHEBI:87715) has part (S)-prasugrel (CHEBI:87724) |
| prasugrel (CHEBI:87715) has role anti-anaemic agent (CHEBI:75835) |
| prasugrel (CHEBI:87715) has role anti-arrhythmia drug (CHEBI:38070) |
| prasugrel (CHEBI:87715) has role anti-asthmatic agent (CHEBI:65023) |
| prasugrel (CHEBI:87715) has role anti-HIV agent (CHEBI:64946) |
| prasugrel (CHEBI:87715) has role anticoagulant (CHEBI:50249) |
| prasugrel (CHEBI:87715) has role antimicrobial agent (CHEBI:33281) |
| prasugrel (CHEBI:87715) has role antiviral agent (CHEBI:22587) |
| prasugrel (CHEBI:87715) has role cardiovascular drug (CHEBI:35554) |
| prasugrel (CHEBI:87715) has role P2Y12 receptor antagonist (CHEBI:68563) |
| prasugrel (CHEBI:87715) has role platelet glycoprotein-IIb/IIIa receptor antagonist (CHEBI:50433) |
| prasugrel (CHEBI:87715) has role prodrug (CHEBI:50266) |
| prasugrel (CHEBI:87715) has role renoprotective agent (CHEBI:231911) |
| prasugrel (CHEBI:87715) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate |
| INN | Source |
|---|---|
| prasugrel | ChemIDplus |
| Synonyms | Source |
|---|---|
| CS 747 | ChemIDplus |
| CS-747 | ChemIDplus |
| rac-prasugrel | ChEBI |
| HSDB 7995 | ChemIDplus |
| (RS)-prasugrel | ChEBI |
| LY 640315 | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| DB06209 | DrugBank |
| HMDB0015625 | HMDB |
| Prasugrel | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:9008623 | Reaxys |
| CAS:150322-43-3 | ChemIDplus |
| Citations |
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