EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:87715 - prasugrel
| ChEBI ID | CHEBI:87715 |
| ChEBI Name | prasugrel |
| Stars | |
| Definition | A racemate comprising equal amounts of (R)- and (S)-prasugrel. Used (as its hydrochloride salt) to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. |
| Last Modified | 22 February 2017 |
| Submitter | Steve |
| Formula | C20H20FNO3S |
| Net Charge | 0 |
| Average Mass | 373.443 |
| Monoisotopic Mass | 373.11479 |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | platelet glycoprotein-IIb/IIIa receptor antagonist Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antiviral agent A substance that destroys or inhibits replication of viruses. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. P2Y12 receptor antagonist An antagonist at the P2Y12 receptor |
| Applications: | platelet glycoprotein-IIb/IIIa receptor antagonist Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. anti-asthmatic agent Any compound that has anti-asthmatic effects. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. anticoagulant An agent that prevents blood clotting. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. renoprotective agent Any compound that is able to prevent damage to the kidneys. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prasugrel (CHEBI:87715) has part (R)-prasugrel (CHEBI:87725) |
| prasugrel (CHEBI:87715) has part (S)-prasugrel (CHEBI:87724) |
| prasugrel (CHEBI:87715) has role anti-anaemic agent (CHEBI:75835) |
| prasugrel (CHEBI:87715) has role anti-arrhythmia drug (CHEBI:38070) |
| prasugrel (CHEBI:87715) has role anti-asthmatic agent (CHEBI:65023) |
| prasugrel (CHEBI:87715) has role anti-HIV agent (CHEBI:64946) |
| prasugrel (CHEBI:87715) has role anticoagulant (CHEBI:50249) |
| prasugrel (CHEBI:87715) has role antimicrobial agent (CHEBI:33281) |
| prasugrel (CHEBI:87715) has role antiviral agent (CHEBI:22587) |
| prasugrel (CHEBI:87715) has role cardiovascular drug (CHEBI:35554) |
| prasugrel (CHEBI:87715) has role P2Y12 receptor antagonist (CHEBI:68563) |
| prasugrel (CHEBI:87715) has role platelet glycoprotein-IIb/IIIa receptor antagonist (CHEBI:50433) |
| prasugrel (CHEBI:87715) has role prodrug (CHEBI:50266) |
| prasugrel (CHEBI:87715) has role renoprotective agent (CHEBI:231911) |
| prasugrel (CHEBI:87715) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate |
| INN | Source |
|---|---|
| prasugrel | ChemIDplus |
| Synonyms | Source |
|---|---|
| CS 747 | ChemIDplus |
| CS-747 | ChemIDplus |
| rac-prasugrel | ChEBI |
| HSDB 7995 | ChemIDplus |
| (RS)-prasugrel | ChEBI |
| LY 640315 | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| DB06209 | DrugBank |
| HMDB0015625 | HMDB |
| Prasugrel | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:9008623 | Reaxys |
| CAS:150322-43-3 | ChemIDplus |
| Citations |
|---|