EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:87681 - ranolazine

ChEBI IDCHEBI:87681
ChEBI Nameranolazine
Stars
DefinitionA racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.
Last Modified22 February 2017
SubmitterSteve
FormulaC24H33N3O4
Net Charge0
Average Mass427.537
Monoisotopic Mass427.24711
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Application:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
ranolazine (CHEBI:87681) has part (R)-ranolazine (CHEBI:87696)
ranolazine (CHEBI:87681) has part (S)-ranolazine (CHEBI:87693)
ranolazine (CHEBI:87681) has role anti-arrhythmia drug (CHEBI:38070)
ranolazine (CHEBI:87681) has role sodium channel blocker (CHEBI:38633)
ranolazine (CHEBI:87681) is a racemate (CHEBI:60911)
IUPAC Name 
rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
INN  Source
ranolazineKEGG DRUG
Synonyms  Source
rac-ranolazineChEBI
(RS)-ranolazineChEBI
(+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamideChemIDplus
racemic ranolazineChEBI
(+-)-RanolazineChemIDplus
Brand Name  Source
RanexaChemIDplus
Manual XrefsDatabases
D05700KEGG DRUG
DB00243DrugBank
EP126449Patent
RanolazineWikipedia
US4567264Patent
Registry NumbersSources
Reaxys:8234797Reaxys
CAS:95635-55-5KEGG DRUG
CAS:95635-55-5ChemIDplus
Citations