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CHEBI:86323 - conazole antifungal agent
| ChEBI ID | CHEBI:86323 |
| ChEBI Name | conazole antifungal agent |
| Stars | |
| Definition | A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. |
| Secondary ChEBI ID | CHEBI:60593 |
| Last Modified | 23 July 2015 |
| Submitter | Gareth Owen |
| Roles Classification |
|---|
| Biological Roles: | ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| conazole antifungal agent (CHEBI:86323) has role antifungal agent (CHEBI:35718) |
| conazole antifungal agent (CHEBI:86323) has role ergosterol biosynthesis inhibitor (CHEBI:75282) |
| conazole antifungal agent (CHEBI:86323) is a azole (CHEBI:68452) |
| Incoming Relation(s) |
| conazole antifungal drug (CHEBI:87071) is a conazole antifungal agent (CHEBI:86323) |
| conazole fungicide (CHEBI:87067) is a conazole antifungal agent (CHEBI:86323) |
| diniconazole-M (CHEBI:83911) is a conazole antifungal agent (CHEBI:86323) |
| Synonyms | Source |
|---|---|
| azole antibiotics | ChEBI |
| azole antibiotic | ChEBI |
| conazole antifungal agents | ChEBI |