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CHEBI:85267 - flumequine
| ChEBI ID | CHEBI:85267 |
| ChEBI Name | flumequine |
| Stars | |
| Definition | A racemate comprising equimolar amounts of R- and S-flumequine. A broad-spectrum antibiotic, formerly used in veterinary medicine for stock breeding and treatment of aquacultures. |
| Last Modified | 19 September 2018 |
| Submitter | Steve |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. topoisomerase IV inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| flumequine (CHEBI:85267) has part (R)-flumequine (CHEBI:85273) |
| flumequine (CHEBI:85267) has part (S)-flumequine (CHEBI:85272) |
| flumequine (CHEBI:85267) has role antimicrobial agent (CHEBI:33281) |
| flumequine (CHEBI:85267) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750) |
| flumequine (CHEBI:85267) has role environmental contaminant (CHEBI:78298) |
| flumequine (CHEBI:85267) has role topoisomerase IV inhibitor (CHEBI:53559) |
| flumequine (CHEBI:85267) has role xenobiotic (CHEBI:35703) |
| flumequine (CHEBI:85267) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid |
| INNs | Source |
|---|---|
| flumequine | KEGG DRUG |
| flumequino | ChemIDplus |
| flumequinum | ChemIDplus |
| Synonym | Source |
|---|---|
| 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| D02302 | KEGG DRUG |
| Flumequine | Wikipedia |
| 1564 | VSDB |
| Registry Numbers | Sources |
|---|---|
| Reaxys:490724 | Reaxys |
| CAS:42835-25-6 | KEGG DRUG |
| CAS:42835-25-6 | ChemIDplus |
| Citations |
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