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CHEBI:85192 - tazobactam sodium

ChEBI IDCHEBI:85192
ChEBI Nametazobactam sodium
Stars
DefinitionAn organic sodium salt having tazobactam(1−) as the counterion; used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Last Modified11 March 2015
SubmitterSteve
DownloadsMolfile
FormulaC10H11N4O5S.Na
Net Charge0
Average Mass322.278
Monoisotopic Mass322.03478
SMILES[H][C@@]12CC(=O)N1[C@@H](C(=O)[O-])[C@](C)(Cn1ccnn1)S2(=O)=O.[Na+]
InChIInChI=1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
InChIKeyRFMIKMMOLPNEDG-QVUDESDKSA-M
Wikipedia
Roles Classification
Biological Roles:
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
EC 3.5.2.6 (beta-lactamase) inhibitor  An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of β-lactamase (EC 3.5.2.6).
Application:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
ChEBI Ontology
Outgoing Relation(s)
tazobactam sodium (CHEBI:85192) has part tazobactam(1−) (CHEBI:85193)
tazobactam sodium (CHEBI:85192) has role antiinfective agent (CHEBI:35441)
tazobactam sodium (CHEBI:85192) has role antimicrobial agent (CHEBI:33281)
tazobactam sodium (CHEBI:85192) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625)
tazobactam sodium (CHEBI:85192) is a organic sodium salt (CHEBI:38700)
Incoming Relation(s)
Zerbaxa (CHEBI:85191) has part tazobactam sodium (CHEBI:85192)
IUPAC Name 
sodium (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Synonyms  Source
Tazobactam sodium saltChemIDplus
CL 307,579ChemIDplus
CL 307579ChemIDplus
2-alpha-Methyl-2-beta-(1,2,3-triazol-1-ylmethyl)penam-3-alpha-carboxylic acid sodium saltChemIDplus
Manual XrefsDatabases
D03707KEGG DRUG
TazobactamWikipedia
DB01606DrugBank
Registry NumbersSources
Reaxys:6039128Reaxys
CAS:89785-84-2KEGG DRUG
CAS:89785-84-2ChemIDplus
Citations