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CHEBI:84340 - hydrazinocurcumin
| Formula | C21H20N2O4 |
| Net Charge | 0 |
| Average Mass | 364.401 |
| Monoisotopic Mass | 364.14231 |
| SMILES | COc1cc(/C=C/c2cc(/C=C/c3ccc(O)c(OC)c3)nn2)ccc1O |
| InChI | InChI=1S/C21H20N2O4/c1-26-20-11-14(5-9-18(20)24)3-7-16-13-17(23-22-16)8-4-15-6-10-19(25)21(12-15)27-2/h3-13,24-25H,1-2H3,(H,22,23)/b7-3+,8-4+ |
| InChIKey | LKLASFRCXLTNMY-FCXRPNKRSA-N |
| Roles Classification |
|---|
| Biological Roles: | EC 2.3.1.48 (histone acetyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. angiogenesis modulating agent An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| hydrazinocurcumin (CHEBI:84340) has functional parent curcumin (CHEBI:3962) |
| hydrazinocurcumin (CHEBI:84340) has role angiogenesis modulating agent (CHEBI:50926) |
| hydrazinocurcumin (CHEBI:84340) has role antineoplastic agent (CHEBI:35610) |
| hydrazinocurcumin (CHEBI:84340) has role EC 2.3.1.48 (histone acetyltransferase) inhibitor (CHEBI:76395) |
| hydrazinocurcumin (CHEBI:84340) has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor (CHEBI:50925) |
| hydrazinocurcumin (CHEBI:84340) is a aromatic ether (CHEBI:35618) |
| hydrazinocurcumin (CHEBI:84340) is a olefinic compound (CHEBI:78840) |
| hydrazinocurcumin (CHEBI:84340) is a polyphenol (CHEBI:26195) |
| hydrazinocurcumin (CHEBI:84340) is a pyrazoles (CHEBI:26410) |
| IUPAC Name |
|---|
| 4,4'-[1H-pyrazole-3,5-diyldi(E)ethene-2,1-diyl]bis(2-methoxyphenol) |
| Synonym | Source |
|---|---|
| pyrazole-curcumin | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:4271395 | Reaxys |
| Citations |
|---|