CHEBI:8428 - procainamide

ChEBI IDCHEBI:8428
ChEBI Nameprocainamide
Stars
DefinitionA benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Last Modified30 April 2018
DownloadsMolfile
FormulaC13H21N3O
Net Charge0
Average Mass235.331
Monoisotopic Mass235.16846
SMILESCCN(CC)CCNC(=O)c1ccc(N)cc1
InChIInChI=1S/C13H21N3O/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17)
InChIKeyREQCZEXYDRLIBE-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Applications:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
ChEBI Ontology
Outgoing Relation(s)
procainamide (CHEBI:8428) has role anti-arrhythmia drug (CHEBI:38070)
procainamide (CHEBI:8428) has role platelet aggregation inhibitor (CHEBI:50427)
procainamide (CHEBI:8428) has role sodium channel blocker (CHEBI:38633)
procainamide (CHEBI:8428) is a benzamides (CHEBI:22702)
Incoming Relation(s)
procainamide hydrochloride (CHEBI:8429) has part procainamide (CHEBI:8428)
IUPAC Name 
4-amino-N-[2-(diethylamino)ethyl]benzamide
INNs  Source
procainamidaChemIDplus
procainamideChemIDplus
procaïnamideChEBI
procainamidumChemIDplus
Synonyms  Source
p-Aminobenzoic diethylaminoethylamideChemIDplus
p-Amino-N-(2-diethylaminoethyl)benzamideChemIDplus
ProcainamideKEGG COMPOUND
Brand Name  Source
BiocorylDrugBank
Manual XrefsDatabases
2270DrugCentral
C07401KEGG COMPOUND
D08421KEGG DRUG
DB01035DrugBank
LSM-3681LINCS
ProcainamideWikipedia
Registry NumbersSources
Reaxys:2214285Reaxys
CAS:51-06-9ChemIDplus
Citations