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CHEBI:82467 - Evans blue

Default Structure
ChEBI IDCHEBI:82467
ChEBI NameEvans blue
Stars
DefinitionAn organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence.
Secondary ChEBI IDCHEBI:87630
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC34H24N6O14S4.4Na
Net Charge0
Average Mass960.822
Monoisotopic Mass959.98241
SMILESCc1cc(-c2ccc(N=Nc3ccc4c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c4c3O)c(C)c2)ccc1N=Nc1ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c2c1O.[Na+].[Na+].[Na+].[Na+]
InChIInChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4
InChIKeyATNOAWAQFYGAOY-UHFFFAOYSA-J
Wikipedia
Roles Classification
Biological Roles:
teratogenic agent  A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Applications:
fluorochrome  A fluorescent dye used to stain biological specimens.
histological dye  A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
ChEBI Ontology
Outgoing Relation(s)
Evans blue (CHEBI:82467) has part Evans blue(4−) (CHEBI:87636)
Evans blue (CHEBI:82467) has role fluorochrome (CHEBI:51217)
Evans blue (CHEBI:82467) has role histological dye (CHEBI:77178)
Evans blue (CHEBI:82467) has role sodium channel blocker (CHEBI:38633)
Evans blue (CHEBI:82467) has role teratogenic agent (CHEBI:50905)
Evans blue (CHEBI:82467) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
tetrasodium 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
Synonyms  Source
4,4'-Bis(1-amino-8-hydroxy-2,4-disulfo-7-naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(1-amino-8-hydroxy-2,4-disulpho-7-naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulpho)naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
azovan blueChEBI
C.I. 23860ChEBI
Manual XrefsDatabases
C19422KEGG COMPOUND
Evans_Blue_(dye)Wikipedia
Registry NumbersSources
Reaxys:7110511Reaxys
CAS:314-13-6ChemIDplus
CAS:314-13-6KEGG COMPOUND
Citations