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CHEBI:82467 - Evans blue

Default Structure
ChEBI IDCHEBI:82467
ChEBI NameEvans blue
Stars
DefinitionAn organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence.
Secondary ChEBI IDCHEBI:87630
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC34H24N6O14S4.4Na
Net Charge0
Average Mass960.822
Monoisotopic Mass959.98241
SMILESCc1cc(-c2ccc(N=Nc3ccc4c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c4c3O)c(C)c2)ccc1N=Nc1ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c2c1O.[Na+].[Na+].[Na+].[Na+]
InChIInChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4
InChIKeyATNOAWAQFYGAOY-UHFFFAOYSA-J
Wikipedia
Roles Classification
Biological Roles:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
teratogenic agent  A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
Applications:
histological dye  A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
fluorochrome  A fluorescent dye used to stain biological specimens.
ChEBI Ontology
Outgoing Relation(s)
Evans blue (CHEBI:82467) has part Evans blue(4−) (CHEBI:87636)
Evans blue (CHEBI:82467) has role fluorochrome (CHEBI:51217)
Evans blue (CHEBI:82467) has role histological dye (CHEBI:77178)
Evans blue (CHEBI:82467) has role sodium channel blocker (CHEBI:38633)
Evans blue (CHEBI:82467) has role teratogenic agent (CHEBI:50905)
Evans blue (CHEBI:82467) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
tetrasodium 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
Synonyms  Source
4,4'-Bis(1-amino-8-hydroxy-2,4-disulfo-7-naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(1-amino-8-hydroxy-2,4-disulpho-7-naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulpho)naphthylazo)-3,3'-bitolyl, tetrasodium saltChemIDplus
azovan blueChEBI
C.I. 23860ChEBI
Manual XrefsDatabases
C19422KEGG COMPOUND
Evans_Blue_(dye)Wikipedia
Registry NumbersSources
Reaxys:7110511Reaxys
CAS:314-13-6ChemIDplus
CAS:314-13-6KEGG COMPOUND
Citations