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CHEBI:8070 - phenobarbital sodium

ChEBI IDCHEBI:8070
ChEBI Namephenobarbital sodium
Stars
DefinitionA barbiturate that is the sodium salt of phenobarbital (barbituric acid substituted at C-5 by ethyl and phenyl groups).
Last Modified11 July 2014
DownloadsMolfile
FormulaC12H11N2O3.Na
Net Charge0
Average Mass254.221
Monoisotopic Mass254.06674
SMILESCCC1(c2ccccc2)C(=O)N=C([O-])NC1=O.[Na+]
InChIInChI=1S/C12H12N2O3.Na/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;/h3-7H,2H2,1H3,(H2,13,14,15,16,17);/q;+1/p-1
InChIKeyWRLGYAWRGXKSKG-UHFFFAOYSA-M
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
phenobarbital sodium (CHEBI:8070) has part phenobarbital (CHEBI:8069)
phenobarbital sodium (CHEBI:8070) is a barbiturates (CHEBI:22693)
phenobarbital sodium (CHEBI:8070) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
sodium 5-ethyl-4,6-dioxo-5-phenyl-1,4,5,6-tetrahydropyrimidin-2-olate
INNs  Source
phenobarbital sodiumChemIDplus
phenobarbital sodiqueChemIDplus
phenobarbitalum natricumChemIDplus
Synonyms  Source
Phenyl-äthyl-barbitursäure natriumChemIDplus
5-Ethyl-5-phenylbarbituric acid sodium saltChemIDplus
Phenobarbital sodium saltChemIDplus
Sodium luminalChemIDplus
Sodium 5-ethyl-5-phenylbarbiturateChemIDplus
Sodium phenobarbitalChemIDplus
Brand Name  Source
Luminal sodiumKEGG DRUG
Manual XrefsDatabases
D00701KEGG DRUG
Registry NumbersSources
Beilstein:3802044Beilstein
CAS:57-30-7ChemIDplus
Citations