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CHEBI:8025 - perindopril erbumine
| Formula | C19H32N2O5.C4H11N |
| Net Charge | 0 |
| Average Mass | 441.613 |
| Monoisotopic Mass | 441.32027 |
| SMILES | CC(C)(C)N.[H][C@@]12CCCC[C@]1([H])N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H](C(=O)O)C2 |
| InChI | InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
| InChIKey | IYNMDWMQHSMDDE-MHXJNQAMSA-N |
| Roles Classification |
|---|
| Biological Role: | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1). |
| Applications: | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1). cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| perindopril erbumine (CHEBI:8025) has part perindopril(1−) (CHEBI:78000) |
| perindopril erbumine (CHEBI:8025) has role antihypertensive agent (CHEBI:35674) |
| perindopril erbumine (CHEBI:8025) has role cardiovascular drug (CHEBI:35554) |
| perindopril erbumine (CHEBI:8025) has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (CHEBI:35457) |
| perindopril erbumine (CHEBI:8025) is a addition compound (CHEBI:35504) |
| IUPAC Name |
|---|
| (2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid—2-methylpropan-2-amine (1/1) |
| Synonyms | Source |
|---|---|
| (2S,3aS,7aS)-1-{(S)-2-[(S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydroindole-2-carboxylic acid—1,1-dimethylethanamine (1/1) | ChEBI |
| (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1) | ChemIDplus |
| MCN-A-2833-109 | ChEMBL |
| NSC-758929 | ChEMBL |
| Perindopril erbumine | KEGG COMPOUND |
| Perindopril tert-butylamine | ChEMBL |
| Brand Names | Source |
|---|---|
| Aceon | DrugBank |
| Perindopril erbumine component of amlessa | ChEMBL |
| Citations |
|---|