EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:8024 - perindopril

Default Structure
ChEBI IDCHEBI:8024
ChEBI Nameperindopril
Stars
DefinitionAn α-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
Last Modified22 February 2017
DownloadsMolfile
FormulaC19H32N2O5
Net Charge0
Average Mass368.474
Monoisotopic Mass368.23112
SMILES[H][C@@]12CCCC[C@]1([H])N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H](C(=O)O)C2
InChIInChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1
InChIKeyIPVQLZZIHOAWMC-QXKUPLGCSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Role:
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
hypoglycemic agent  A drug which lowers the blood glucose level.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
ChEBI Ontology
Outgoing Relation(s)
perindopril (CHEBI:8024) has role antidepressant (CHEBI:35469)
perindopril (CHEBI:8024) has role antihypertensive agent (CHEBI:35674)
perindopril (CHEBI:8024) has role antineoplastic agent (CHEBI:35610)
perindopril (CHEBI:8024) has role cardiovascular drug (CHEBI:35554)
perindopril (CHEBI:8024) has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (CHEBI:35457)
perindopril (CHEBI:8024) has role hypoglycemic agent (CHEBI:35526)
perindopril (CHEBI:8024) is a dicarboxylic acid monoester (CHEBI:36244)
perindopril (CHEBI:8024) is a ethyl ester (CHEBI:23990)
perindopril (CHEBI:8024) is a organic heterobicyclic compound (CHEBI:27171)
perindopril (CHEBI:8024) is a α-amino acid ester (CHEBI:46874)
perindopril (CHEBI:8024) is conjugate acid of perindopril(1−) (CHEBI:78000)
Incoming Relation(s)
perindopril(1−) (CHEBI:78000) is conjugate base of perindopril (CHEBI:8024)
IUPAC Name 
ethyl N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvalinate
INNs  Source
perindoprilChemIDplus
perindoprilumChemIDplus
Synonyms  Source
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acidIUPAC
MCN-A-2833ChEMBL
S-9490ChEMBL
Manual XrefsDatabases
2108DrugCentral
C07706KEGG COMPOUND
D03753KEGG DRUG
DB00790DrugBank
HMDB0014928HMDB
LSM-4080LINCS
PerindoprilWikipedia
Registry NumbersSources
Reaxys:4300272Reaxys
CAS:82834-16-0ChemIDplus
CAS:82834-16-0KEGG COMPOUND
Citations