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CHEBI:7944 - paroxetine hydrochloride
| Formula | C19H20FNO3.HCl |
| Net Charge | 0 |
| Average Mass | 365.832 |
| Monoisotopic Mass | 365.11940 |
| SMILES | [H]Cl.[H][C@@]1(c2ccc(F)cc2)CCNC[C@H]1COc1ccc2c(c1)OCO2 |
| InChI | InChI=1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1 |
| InChIKey | GELRVIPPMNMYGS-RVXRQPKJSA-N |
| Roles Classification |
|---|
| Biological Roles: | hepatotoxic agent A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| Applications: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| paroxetine hydrochloride (CHEBI:7944) has part paroxetinium(1+) (CHEBI:64197) |
| paroxetine hydrochloride (CHEBI:7944) has role antidepressant (CHEBI:35469) |
| paroxetine hydrochloride (CHEBI:7944) has role anxiolytic drug (CHEBI:35474) |
| paroxetine hydrochloride (CHEBI:7944) has role hepatotoxic agent (CHEBI:50908) |
| paroxetine hydrochloride (CHEBI:7944) has role P450 inhibitor (CHEBI:50183) |
| paroxetine hydrochloride (CHEBI:7944) has role serotonin uptake inhibitor (CHEBI:50949) |
| paroxetine hydrochloride (CHEBI:7944) is a hydrochloride (CHEBI:36807) |
| IUPAC Name |
|---|
| (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride |
| Synonyms | Source |
|---|---|
| paroxetine HCl | ChemIDplus |
| paroxetine hydrochloride anhydrous | DrugBank |
| Brand Names | Source |
|---|---|
| Aropax | ChEBI |
| Paroxat | ChemIDplus |
| Paxil | KEGG DRUG |
| Seroxat | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| D05374 | KEGG DRUG |
| DBSALT000132 | DrugBank |
| US2005191350 | Patent |
| WO2009138999 | Patent |
| Registry Numbers | Sources |
|---|---|
| CAS:78246-49-8 | ChemIDplus |
| Citations |
|---|