CHEBI:7935 - paromomycin sulfate

ChEBI IDCHEBI:7935
ChEBI Nameparomomycin sulfate
Stars
DefinitionAn aminoglycoside sulfate salt resulting from the treatment of paromomycin with sulfuric acid. A broad-spectrum antibiotic, it is used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.
Last Modified25 May 2012
DownloadsMolfile
Formula(H2O4S)n.C23H45N5O14
Net Charge0
Average Mass713.713
Monoisotopic Mass713.26368
SMILESNC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O.O=S(=O)(O)O
InChIInChI=1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
InChIKeyLJRDOKAZOAKLDU-UDXJMMFXSA-N
Wikipedia
Roles Classification
Biological Roles:
antiprotozoal drug  Any antimicrobial drug which is used to treat or prevent protozoal infections.
antileishmanial agent  An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
antibacterial drug  A drug used to treat or prevent bacterial infections.
Applications:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
anthelminthic drug  Substance intended to kill parasitic worms (helminths).
antiprotozoal drug  Any antimicrobial drug which is used to treat or prevent protozoal infections.
antiamoebic agent  An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
antiparasitic agent  A substance used to treat or prevent parasitic infections.
antileishmanial agent  An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
antibacterial drug  A drug used to treat or prevent bacterial infections.
ChEBI Ontology
Outgoing Relation(s)
paromomycin sulfate (CHEBI:7935) has functional parent paromomycin (CHEBI:7934)
paromomycin sulfate (CHEBI:7935) has role anthelminthic drug (CHEBI:35443)
paromomycin sulfate (CHEBI:7935) has role antiamoebic agent (CHEBI:171664)
paromomycin sulfate (CHEBI:7935) has role antibacterial drug (CHEBI:36047)
paromomycin sulfate (CHEBI:7935) has role antiinfective agent (CHEBI:35441)
paromomycin sulfate (CHEBI:7935) has role antileishmanial agent (CHEBI:70868)
paromomycin sulfate (CHEBI:7935) has role antiparasitic agent (CHEBI:35442)
paromomycin sulfate (CHEBI:7935) has role antiprotozoal drug (CHEBI:35820)
paromomycin sulfate (CHEBI:7935) is a aminoglycoside sulfate salt (CHEBI:38012)
IUPAC Name 
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside sulfate
Synonyms  Source
aminosidine sulfateChemIDplus
aminosidine sulphateChemIDplus
aminosidin sulfateChemIDplus
NSC-758421ChEMBL
Brand Names  Source
AminoxidinChEMBL
FarmiglucinChEMBL
FarminosidinChEMBL
GabbromicinaChEMBL
GabbromycinChEMBL
GabbroralChEMBL
Manual XrefsDatabases
D00868KEGG DRUG
DB01421DrugBank
Paromomycin_sulfateWikipedia
Registry NumbersSources
Reaxys:21343285Reaxys
CAS:1263-89-4ChemIDplus
CAS:1263-89-4KEGG DRUG
Citations