EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
We are looking for a new Chemistry curator to join the ChEBI team. Find out more about it here.
CHEBI:7823 - oxazepam
| Formula | C15H11ClN2O2 |
| Net Charge | 0 |
| Average Mass | 286.718 |
| Monoisotopic Mass | 286.05091 |
| SMILES | O=C1Nc2ccc(Cl)cc2C(c2ccccc2)=NC1O |
| InChI | InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19) |
| InChIKey | ADIMAYPTOBDMTL-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| oxazepam (CHEBI:7823) has role anti-HIV agent (CHEBI:64946) |
| oxazepam (CHEBI:7823) has role antidepressant (CHEBI:35469) |
| oxazepam (CHEBI:7823) has role antipsychotic agent (CHEBI:35476) |
| oxazepam (CHEBI:7823) has role anxiolytic drug (CHEBI:35474) |
| oxazepam (CHEBI:7823) has role environmental contaminant (CHEBI:78298) |
| oxazepam (CHEBI:7823) has role xenobiotic (CHEBI:35703) |
| oxazepam (CHEBI:7823) is a 1,4-benzodiazepinone (CHEBI:35500) |
| oxazepam (CHEBI:7823) is a organochlorine compound (CHEBI:36683) |
| IUPAC Name |
|---|
| 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| Synonyms | Source |
|---|---|
| J3.308A | ChEMBL |
| NSC-169448 | ChEMBL |
| (+-)-Oxazepam | ChemIDplus |
| Oxazepam | KEGG COMPOUND |
| Oxazepam civ | ChEMBL |
| Oxozepam | ChEMBL |
| Brand Names | Source |
|---|---|
| Lederpam | ChEMBL |
| Serenid fte | ChEMBL |
| Citations |
|---|