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CHEBI:77829 - rac-nortilidine
| ChEBI ID | CHEBI:77829 |
| ChEBI Name | rac-nortilidine |
| Stars | |
| ASCII Name | rac-nortilidine |
| Definition | A racemate comprising (1R,2S)- and (1S,2R)-nortilidine. The synthetic narcotic analgesic tilidine is a prodrug for nortilidine, being metabolised to it in the liver. Virtually all of the opioid analgesic effects of racemic nortilidine, which are comparable to those of morphine, are due to the (1S,2R) enantiomer. |
| Last Modified | 17 April 2014 |
| Submitter | Gareth Owen |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. |
| Application: | opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| rac-nortilidine (CHEBI:77829) has part (1R,2S)-nortilidine (CHEBI:77841) |
| rac-nortilidine (CHEBI:77829) has part (1S,2R)-nortilidine (CHEBI:77839) |
| rac-nortilidine (CHEBI:77829) has role drug metabolite (CHEBI:49103) |
| rac-nortilidine (CHEBI:77829) has role opioid analgesic (CHEBI:35482) |
| rac-nortilidine (CHEBI:77829) is a racemate (CHEBI:60911) |
| IUPAC Names |
|---|
| rac-ethyl (1S,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate |
| rac-ethyl (1R,2S)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate |
| Synonyms | Source |
|---|---|
| nortilidine | ChEBI |
| (±)-ethyl trans-2-methylamino-1-phenyl-3-cyclohexene-trans-1-carboxylate | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| Nortilidine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:4145877 | Reaxys |
| CAS:38677-94-0 | ChemIDplus |
| Citations |
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