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CHEBI:7772 - omeprazole
| ChEBI ID | CHEBI:7772 |
| ChEBI Name | omeprazole |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-omeprazole. |
| Last Modified | 19 September 2018 |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) |
| Roles Classification |
|---|
| Biological Roles: | human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. |
| Applications: | anticonvulsant A drug used to prevent seizures or reduce their severity. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| omeprazole (CHEBI:7772) has part (R)-omeprazole (CHEBI:77262) |
| omeprazole (CHEBI:7772) has part esomeprazole (CHEBI:50275) |
| omeprazole (CHEBI:7772) has role anti-ulcer drug (CHEBI:49201) |
| omeprazole (CHEBI:7772) has role anticonvulsant (CHEBI:35623) |
| omeprazole (CHEBI:7772) has role EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200) |
| omeprazole (CHEBI:7772) has role human metabolite (CHEBI:77746) |
| omeprazole (CHEBI:7772) has role P450 inhibitor (CHEBI:50183) |
| omeprazole (CHEBI:7772) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| 5'-hydroxyomeprazole (CHEBI:63840) has functional parent omeprazole (CHEBI:7772) |
| Yosprala (CHEBI:134674) has part omeprazole (CHEBI:7772) |
| IUPAC Name |
|---|
| rac-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole |
| INNs | Source |
|---|---|
| omeprazol | ChemIDplus |
| omeprazole | ChemIDplus |
| omeprazolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole | ChEBI |
| OMEP | DrugBank |
| OMP | DrugBank |
| OMZ | DrugBank |
| Brand Names | Source |
|---|---|
| Antra | DrugBank |
| Audazol | DrugBank |
| Belmazol | DrugBank |
| Ceprandal | DrugBank |
| Danlox | DrugBank |
| Desec | DrugBank |
| Registry Numbers | Sources |
|---|---|
| Reaxys:3628192 | Reaxys |
| CAS:73590-58-6 | ChemIDplus |
| Citations |
|---|