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CHEBI:7772 - omeprazole
| ChEBI ID | CHEBI:7772 |
| ChEBI Name | omeprazole |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-omeprazole. |
| Last Modified | 19 September 2018 |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) |
| Roles Classification |
|---|
| Biological Roles: | EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. |
| Applications: | anticonvulsant A drug used to prevent seizures or reduce their severity. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| omeprazole (CHEBI:7772) has part (R)-omeprazole (CHEBI:77262) |
| omeprazole (CHEBI:7772) has part esomeprazole (CHEBI:50275) |
| omeprazole (CHEBI:7772) has role anti-ulcer drug (CHEBI:49201) |
| omeprazole (CHEBI:7772) has role anticonvulsant (CHEBI:35623) |
| omeprazole (CHEBI:7772) has role EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200) |
| omeprazole (CHEBI:7772) has role human metabolite (CHEBI:77746) |
| omeprazole (CHEBI:7772) has role P450 inhibitor (CHEBI:50183) |
| omeprazole (CHEBI:7772) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| 5'-hydroxyomeprazole (CHEBI:63840) has functional parent omeprazole (CHEBI:7772) |
| Yosprala (CHEBI:134674) has part omeprazole (CHEBI:7772) |
| IUPAC Name |
|---|
| rac-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole |
| INNs | Source |
|---|---|
| omeprazole | ChemIDplus |
| omeprazol | ChemIDplus |
| omeprazolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| OMEP | DrugBank |
| 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole | ChEBI |
| OMZ | DrugBank |
| OMP | DrugBank |
| Brand Names | Source |
|---|---|
| Antra | DrugBank |
| Audazol | DrugBank |
| Belmazol | DrugBank |
| Ceprandal | DrugBank |
| Danlox | DrugBank |
| Desec | DrugBank |
| Registry Numbers | Sources |
|---|---|
| Reaxys:3628192 | Reaxys |
| CAS:73590-58-6 | ChemIDplus |
| Citations |
|---|