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| ChEBI ID | CHEBI:7772 |
| ChEBI Name | omeprazole |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-omeprazole. |
| Last Modified | 19 September 2018 |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) |
| Roles Classification |
|---|
| Biological Roles: | human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antiviral agent A substance that destroys or inhibits replication of viruses. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors. anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. |
| Applications: | vulnerary A drug used in treating and healing of wounds. anti-inflammatory agent Any compound that has anti-inflammatory effects. anticonvulsant A drug used to prevent seizures or reduce their severity. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. hypoglycemic agent A drug which lowers the blood glucose level. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antipsoriatic A drug used to treat psoriasis. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. antirheumatic drug A drug used to treat rheumatoid arthritis. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. vasodilator agent A drug used to cause dilation of the blood vessels. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antifibrotic agent Any agent which acts to reduce fibrosis. antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| omeprazole (CHEBI:7772) has part (R)-omeprazole (CHEBI:77262) |
| omeprazole (CHEBI:7772) has part esomeprazole (CHEBI:50275) |
| omeprazole (CHEBI:7772) has role analgesic (CHEBI:35480) |
| omeprazole (CHEBI:7772) has role anti-anaemic agent (CHEBI:75835) |
| omeprazole (CHEBI:7772) has role anti-HBV agent (CHEBI:64951) |
| omeprazole (CHEBI:7772) has role anti-HIV agent (CHEBI:64946) |
| omeprazole (CHEBI:7772) has role anti-inflammatory agent (CHEBI:67079) |
| omeprazole (CHEBI:7772) has role anti-ulcer drug (CHEBI:49201) |
| omeprazole (CHEBI:7772) has role antibacterial agent (CHEBI:33282) |
| omeprazole (CHEBI:7772) has role anticonvulsant (CHEBI:35623) |
| omeprazole (CHEBI:7772) has role antifibrotic agent (CHEBI:233423) |
| omeprazole (CHEBI:7772) has role antiglaucoma drug (CHEBI:39456) |
| omeprazole (CHEBI:7772) has role antiinfective agent (CHEBI:35441) |
| omeprazole (CHEBI:7772) has role antineoplastic agent (CHEBI:35610) |
| omeprazole (CHEBI:7772) has role antipsoriatic (CHEBI:50748) |
| omeprazole (CHEBI:7772) has role antirheumatic drug (CHEBI:35842) |
| omeprazole (CHEBI:7772) has role antitussive (CHEBI:51177) |
| omeprazole (CHEBI:7772) has role antiviral agent (CHEBI:22587) |
| omeprazole (CHEBI:7772) has role dermatologic drug (CHEBI:50177) |
| omeprazole (CHEBI:7772) has role EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200) |
| omeprazole (CHEBI:7772) has role human metabolite (CHEBI:77746) |
| omeprazole (CHEBI:7772) has role hypoglycemic agent (CHEBI:35526) |
| omeprazole (CHEBI:7772) has role immunosuppressive agent (CHEBI:35705) |
| omeprazole (CHEBI:7772) has role P450 inhibitor (CHEBI:50183) |
| omeprazole (CHEBI:7772) has role vasodilator agent (CHEBI:35620) |
| omeprazole (CHEBI:7772) has role vulnerary (CHEBI:73336) |
| omeprazole (CHEBI:7772) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| 5'-hydroxyomeprazole (CHEBI:63840) has functional parent omeprazole (CHEBI:7772) |
| Yosprala (CHEBI:134674) has part omeprazole (CHEBI:7772) |
| IUPAC Name |
|---|
| rac-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole |
| INNs | Source |
|---|---|
| omeprazol | ChemIDplus |
| omeprazole | ChemIDplus |
| omeprazolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole | ChEBI |
| H 168/68 | ChEMBL |
| H-168/68 | ChEMBL |
| NSC-751450 | ChEMBL |
| NSC-759192 | ChEMBL |
| OMEP | DrugBank |
| Brand Names | Source |
|---|---|
| Antra | DrugBank |
| Audazol | DrugBank |
| Belmazol | DrugBank |
| Ceprandal | DrugBank |
| Danlox | DrugBank |
| Desec | DrugBank |
| Registry Numbers | Sources |
|---|---|
| Reaxys:3628192 | Reaxys |
| CAS:73590-58-6 | ChemIDplus |
| Citations |
|---|