CHEBI:77655 - perindopril arginine

ChEBI IDCHEBI:77655
ChEBI Nameperindopril arginine
Stars
DefinitionAn organoammonium salt obtained by combining perindopril with one molar equivalent of L-arginine.
Last Modified11 June 2015
SubmitterRomin
DownloadsMolfile
FormulaC19H32N2O5.C6H14N4O2
Net Charge0
Average Mass542.678
Monoisotopic Mass542.34280
SMILESN=C(N)NCCC[C@H](N)C(=O)O.[H][C@@]12CCCC[C@]1([H])N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H](C(=O)O)C2
InChIInChI=1S/C19H32N2O5.C6H14N4O2/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;7-4(5(11)12)2-1-3-10-6(8)9/h12-16,20H,4-11H2,1-3H3,(H,23,24);4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t12-,13-,14-,15-,16-;4-/m00/s1
InChIKeyRYCSJJXKEWBUTI-YDYAIEMNSA-N
Wikipedia
Roles Classification
Biological Role:
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
Applications:
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
perindopril arginine (CHEBI:77655) has part L-argininium(1+) (CHEBI:32682)
perindopril arginine (CHEBI:77655) has part perindopril(1−) (CHEBI:78000)
perindopril arginine (CHEBI:77655) has role antihypertensive agent (CHEBI:35674)
perindopril arginine (CHEBI:77655) has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (CHEBI:35457)
perindopril arginine (CHEBI:77655) is a organoammonium salt (CHEBI:46850)
Incoming Relation(s)
Prestalia (CHEBI:85999) has part perindopril arginine (CHEBI:77655)
Synonym  Source
perindopril L-arginine saltChEBI
Brand Name  Source
CoversylChemIDplus
Manual XrefsDatabases
US2013178464Patent
US2009203758Patent
EP2161257Patent
PerindoprilWikipedia
NZ570366Patent
RS51431Patent
IL164424Patent
PT2016051EPatent
Registry NumbersSources
Reaxys:19333045Reaxys
CAS:612548-45-5ChemIDplus
Citations