CHEBI:76452 - dialuric acid

ChEBI IDCHEBI:76452
ChEBI Namedialuric acid
Stars
DefinitionA member of the class of barbiturates that is barbituric acid in which a hydrogen attached to a ring carbon is replaced by a hydroxy group.
Last Modified30 January 2020
SubmitterKAX
DownloadsMolfile
FormulaC4H4N2O4
Net Charge0
Average Mass144.086
Monoisotopic Mass144.01711
SMILESO=C1NC(=O)C(O)C(=O)N1
InChIInChI=1S/C4H4N2O4/c7-1-2(8)5-4(10)6-3(1)9/h1,7H,(H2,5,6,8,9,10)
InChIKeyBVEWMNTVZPFPQI-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
dialuric acid (CHEBI:76452) has functional parent barbituric acid (CHEBI:16294)
dialuric acid (CHEBI:76452) is a barbiturates (CHEBI:22693)
dialuric acid (CHEBI:76452) is conjugate acid of dialurate (CHEBI:140629)
Incoming Relation(s)
dialurate (CHEBI:140629) is conjugate base of dialuric acid (CHEBI:76452)
IUPAC Name 
5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione
Synonyms  Source
5-hydroxybarbituric acidChemIDplus
2,4,5,6-pyrimidinetetrolChemIDplus
5-alloxanolChEBI
Manual XrefsDatabases
CPD-15999MetaCyc
Registry NumbersSources
Reaxys:135130Reaxys
Reaxys:131990Reaxys
CAS:444-15-5ChemIDplus
CAS:444-15-5NIST Chemistry WebBook
Citations