EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:140629 - dialurate

ChEBI IDCHEBI:140629
ChEBI Namedialurate
Stars
DefinitionA barbiturate anion resulting from deprotonation of the carbon bearing the hydroxy group of dialuric acid. Major microspecies at pH 7.3
Last Modified31 January 2020
SubmitterAnne Morgat
DownloadsMolfile
FormulaC4H3N2O4
Net Charge-1
Average Mass143.078
Monoisotopic Mass143.00983
SMILESO=c1nc(=O)[c-](O)c(=O)n1
InChIInChI=1S/C4H3N2O4/c7-1-2(8)5-4(10)6-3(1)9/h7H,(H2,5,6,8,9,10)/q-1
InChIKeyOYSYBUXEAFXXMH-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
dialurate (CHEBI:140629) is a barbiturate anion (CHEBI:22691)
dialurate (CHEBI:140629) is conjugate base of dialuric acid (CHEBI:76452)
Incoming Relation(s)
dialuric acid (CHEBI:76452) is conjugate acid of dialurate (CHEBI:140629)
UniProt Name  Source
dialurateUniProt
Manual XrefsDatabases
CPD-15999MetaCyc
Citations